The Zion Williams led Duke Blue Devils are the #1 Overall seed in the NCAA tournament. Odds makers have favored Duke all season and they aren't stopping now, via BetOnline Duke is +225 to win the tournament. Gonzaga has the 2nd best odds at +600.
As of 7:45 PM on Sunday Evening via Betonline:
Duke +225
Gonzaga +600
Virginia +800
Michigan +1000
Kentucky +1200
Michigan State +1200
North Carolina +1200
Tennessee +1400
Auburn +2000
Houston +2500
Nevada +2500
Purdue +2500
Texas Tech +2500
Florida State +3300
Iowa State +3300
LSU +3300
Villanova +3300
Kansas +4000
Virginia Tech +4000
Buffalo +5000
Cincinnati +5000
Kansas State +5000
Marquette +5000
Wisconsin +5000
Baylor +6600
Other Sources of course vary slightly, but they all agree with Duke being a big favorite.
#1 Seeds have won 21 of the 34 NCAA Tournaments since the field expanded in 1985.